Efficacy and safety of 5-grass-pollen sublingual immunotherapy tablets in pediatric allergic rhinoconjunctivitis

Ulrich Wahn, MD; Ana Tabar, MD; Piotr Kuna, MD; Susanne Halken, MD, DMSc; Armelle Montagut, PhD; Olivier de Beaumont, MD; Martine Le Gall, MD

Published on the web site of the American Academy of Allergy, Asthma & Immunology.

A recent study showed that sublingual immunotherapy (SLIT) using a 300IR dose of five-grass pollens which was taken as a tablet that dissolved under the tongue was effective in treating grass pollen allergic rhinitis in adults. In a study to be published in the January issue of The Journal of Allergy and Clinical Immunology, Wahn, et al., tested this same dose of five-grass pollen tablets in treating rhinoconjunctivitis in a pediatric population. The 278 children studied were given either a once-daily dose of SLIT tablets that contained active grass allergens or placebo.

No serious side effects were reported. The authors’ findings show that 300IR five-grass pollen SLIT tablets is a safe and effective way to treat children and adolescents with grass pollen rhinoconjunctivitis and the relief takes effect in the first treatment season.

http://www.aaaai.org/media/jaci/content.asp?contentid=8382