Specific immunotherapy is highly effective for treatment of seasonal allergic rhinitis, particularly where symptomatic medications have proved ineffective or their use is limited by side effects. A major advantage of subcutaneous immunotherapy is the induction of long-term clinical and immunologic tolerance for years after discontinuation. Now it has been demonstrated, using the sublingual route that long-term tolerance similarly can be achieved.
http://www.aaaai.org/global/latest-research-summaries/Current-JACI-Research/disease-modification-allergic-rhinoconjunctivit.aspx
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