March 28, 2012 (Orlando, Florida) — Children who undergo a prolonged trial of sublingual immunotherapy (SLIT) before undertaking oral immunotherapy (OIT) for milk allergy have fewer treatment-related symptoms, particularly severe ones, than those on OIT alone, according to a study reported here at the American Academy of Allergy, Asthma and Immunology (AAAAI) 2012 Annual Meeting.
"We found that prolonged SLIT before OIT improved safety and reduced severe symptoms but did not eliminate all symptoms." There was also no difference in food-challenge thresholds, reported Shannon Seopaul, a research assistant at Johns Hopkins University in Baltimore, Maryland. "At this time, we can't say that prolonged SLIT before OIT is any more effective than OIT itself."
The study was part of a larger study that compared SLIT alone with SLIT followed by OIT (J Allergy Clin Immunol. 2012;129:448-455).
http://www.medscape.com/viewarticle/761136
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Mother and daughter getting allergy skin tests. Click on the photo to see a You Tube interview with another parent and child.
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